This supplement has potential as a treatment in several conditions, but more research is needed to determine the appropriate dosage and interactions with various other supplements and medications.
ADHD --Treatment with carnitine decreased attention problems and aggressive behavior in boys with ADHD.
Diabetes - Oral administration of L-carnitine reduces oxidized LDL cholesterol levels in patients with type 2 diabetes.
Exercise -- Carnitine improves recovery after heavy exercise. Carnitine may be of use in improving exercise capacity of people with peripheral arterial disease. Carnitine moderately improves the duration of exercise and time to recovery in patients with chronic stable angina.
Fatigue -- Carnitine may improve fatigue in certain conditions, including cancer patients receiving chemotherapy. Carnitine decreases the severity and type of fatigue induced by interferon-alpha in the treatment of patients with hepatitis C. Administration of carnitine to healthy elderly subjects results in a reduction of total fat mass, an increase of total muscle mass, and appears to exert a favorable effect on fatigue and serum lipids.
Fertility -- Carnitine and acetyl carnitine therapy are effective in increasing fertility and sperm-semen quality.
Heart Failure -- Those with heart failure may benefit from carnitine supplements.
Hyperthyroidism -- Carnitine is effective in both reversing and preventing symptoms of hyperthyroidism and has a beneficial effect on bone mineralization. Because hyperthyroidism depletes the body deposits of carnitine and since carnitine has little toxicity, teratogenicity, contraindications and few interactions with drugs, carnitine can be of clinical use.
Kidney dialysis -- Intravenous carnitine is an accepted pharmaceutical treatment for carnitine deficiency in end-stage renal disease in patients undergoing dialysis.
Liver cirrhosis -- Treatment of patients with liver cirrhosis with signs of liver insufficiency is complex and seldom satisfactory. Carnitine is involved in liver lipid metabolism and thus might be a potentially effective nutrient. One study shows L carnitine lowers serum ammonia concentration and improves lipid metabolism in patients with liver cirrhosis. Carnitine may also play a beneficial role in the treatment of mild or moderate hepatic encephalopathy, and perhaps liver cancer.
Sexual health -- Apparently l carnitine is helpful in sexual enhancement. Acetyl-l-carnitine is also helpful in this regard.
Thalassemia -- Lcarnitine may be an effective substance for improving the cardiac status of thalassemic patients.
Weight Loss -- The combination of l carnitine, choline, and caffeine has a mild effect on weight loss.