Results can also take far longer with tretinoin than with other treatments, requiring at least six months or so before improvement is seen.
Because of this, tretinoin is generally not recommended as the only option for skin discoloration but it can be used in combination with other effective topicals (source: eMedicine Journal,, November 15, 2001, Volume 2, Number 11). Even though tretinoin can be disappointing for skin lightening, that should in no way diminish the role it plays in the improvement in skin"s cell production, collagen production, elasticity, texture, and dermal thickness. Tretinoin, combined with more effective skin-lightening treatments, is a powerful alliance in the battle against sun-damaged and aged skin.


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